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Single-cell analysis of T-cell responses in vitro and in vivo: role of costimulatory signals

✍ Scribed by A Wells; H Gudmundsdottir; M Walsh; L.A Turka

Book ID: 117237598
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 70 KB
Volume: 31
Category: Article
ISSN: 0041-1345
DOI: 10.1016/s0041-1345(98)01784-9

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## Abstract Suppression of the antibody response by supraoptimal numbers of T helper cells was studied __in vitro__ and found to have both a specific and a nonspecific component. Suppression did not depend on direct cell contract of T and B cells, as supernatants of activated T cells were just as i