## Abstract ## Objective To assess the efficacy and safety of gabapentin in patients with fibromyalgia. ## Methods A 12βweek, randomized, doubleβblind study was designed to compare gabapentin (1,200β2,400 mg/day) (n = 75 patients) with placebo (n = 75 patients) for efficacy and safety in treatin
Single-blind, placebo-controlled multicenter trial of vigabatrin in the treatment of epilepsy
β Scribed by The Italian Study Group on Vigabatrin; C. Loeb; A. Iudice; E. Percucca; A. Gnanasakthy; F. Angeleri; O. Scarpino; G. Avanzini; D. Binelli; A. Baruzzi; G. Procaccianti; B. Bergamasco; C. Bianco; R. Canger; R. Mai; R. Perri; F. Pisani; L. Cocito; M. Manfredi; M. T. Faedda; R. Mutani; M. Gianelli; A. Tartara; E. Perucca; C. A. Tassinari; R. Michelucci; R. Zappoli; G. Zaccara; A. Gnanasakthy; A. Iudice; J. Matthews; J. P. Mumford
- Publisher
- Springer Milan
- Year
- 1992
- Tongue
- English
- Weight
- 549 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1590-1874
No coin nor oath required. For personal study only.
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Fibromyalgia syndrome is a systemic disorder of widespread pain which is thought to result from abnormal pain processing within the central nervous system. There are no currently approved treatments for this indication. Antidepressants appear, however, to be effective, especially those with an actio
## Abstract ## Objective Interleukinβ6 (ILβ6) is a pleiotropic cytokine that regulates the immune response, inflammation, and hematopoiesis. Overproduction of ILβ6 plays pathologic roles in rheumatoid arthritis (RA), and the blockade of ILβ6 may be therapeutically effective for the disease. This s