Heparin rapidly and selectively regulate
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Ketu Mishra-Gorur; John J. Castellot Jr.
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Article
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1999
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John Wiley and Sons
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English
β 261 KB
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Aberrant vascular smooth muscle cell (VSMC) hyperplasia is the hallmark of atherosclerosis and restenosis seen after vascular surgery. Heparin inhibits VSMC proliferation in animal models and in cell culture. To test our hypothesis that heparin mediates its antiproliferative effect by altering phosp