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Simvastatin stimulates VEGF release via p44/p42 MAP kinase in vascular smooth muscle cells

✍ Scribed by Motoki Takenaka; Kouseki Hirade; Kumiko Tanabe; Shigeru Akamatsu; Shuji Dohi; Hiroyuki Matsuno; Osamu Kozawa

Book ID
117053207
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
162 KB
Volume
301
Category
Article
ISSN
0006-291X

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## Abstract Although it is known that transforming growth factor (TGF)‐β induces vascular endothelial growth factor (VEGF) synthesis in vascular smooth muscle cells, the underlying mechanisms are still poorly understood. In the present study, we examined whether the mitogen‐activated protein (MAP)