Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation

Galantamine enhancement of long-term pot

Galantamine enhancement of long-term potentiation is mediated by calcium/calmodulin-dependent protein kinase II and protein kinase C activation

✍ Shigeki Moriguchi; Norifumi Shioda; Feng Han; Jay Z. Yeh; Toshio Narahashi; Kohj 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 652 KB

## Abstract Galantamine, a novel Alzheimer's drug, is known to inhibit acetylcholinesterase activity and potentiate nicotinic acetylcholine receptor (nAChR) in the brain. We previously reported that galantamine potentiates the NMDA‐induced currents in primary cultured rat cortical neurons. We now s