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Simvastatin Inhibits IFN Regulatory Factor 4 Expression and Th17 Cell Differentiation in CD4+ T Cells Derived from Patients with Multiple Sclerosis

✍ Scribed by Zhang, X.; Tao, Y.; Troiani, L.; Markovic-Plese, S.


Book ID
115464286
Publisher
American Association of Immunologists
Year
2011
Tongue
English
Weight
1015 KB
Volume
187
Category
Article
ISSN
0022-1767

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## Abstract Accumulating evidence indicates an immunosuppressive role for CD4^+^CD25^+^ regulatory T cells (Tregs) in autoimmune diseases. Although an impaired Treg function in patients with relapsing‐remitting multiple sclerosis (RR‐MS) has been reported recently, no information is available so fa