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Simvastatin induces interleukin-18 production in human peripheral blood mononuclear cells

✍ Scribed by Hideo Kohka Takahashi; Shuji Mori; Hiromi Iwagaki; Tadashi Yoshino; Noriaki Tanaka; Masahiro Nishibori


Book ID
116366349
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
160 KB
Volume
116
Category
Article
ISSN
1090-2341

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Interleukin-1 (IL-1) production by periodic acid (H5IO6)-oxidized human peripheral blood mononuclear (PBMN) cells was assessed by the thymocyte co-mitogenesis assay. Maximum IL-1 levels (approximately 1.2 U/ml) in the conditioned media of PBMN cells were registered within the first 24 hrs post-oxida