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Simvastatin induces estrogen receptor-alpha (ER-α) in murine bone marrow stromal cells

✍ Scribed by Chunli Song; Jingying Wang; Quansheng Song; Xu Li; Zhongqiang Chen; Qingjun Ma; Zhongjun Liu; Hongti Jia; Gengting Dang

Book ID
106231023
Publisher
Springer
Year
2008
Tongue
English
Weight
251 KB
Volume
26
Category
Article
ISSN
0914-8779

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## Abstract Estrogen plays a critical role in bone metabolism in both sexes. While the major action of estrogen is to inhibit bone resorption, it is now clear that early osteoblastic (or stromal) cells are a target for estrogen action, mediating the effects of estrogen on bone formation as well as