Oxygen/drug supply to cancer cells is an important factor defining response to radiotherapy and chemotherapy. Although tumor angiogenesis is considered an important prognostic marker, its role in the outcome of chemotherapy and radiotherapy is unknown. In the present study we examined the possible c
Simultaneous versus sequential combined technique therapy for squamous cell head and neck cancer
β Scribed by David J. Adelstein; Vishwa M. Sharan; A. Scott Earle; Ajit C. Shah; Catherine Vlastou; Chandra D. Haria; Catherine Damm; Susan G. Carter; John D. Hines
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 645 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0008-543X
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## Abstract Combined simultaneous radiotherapy and multidrug chemotherapy have been utilized in an attempt to eradicate or shrink tumors of the head and neck area in advanced stages to allow subsequent surgical extirpation. Thirtyβsix patients (1 stage II; 11 stage III; 24 stage IV; 1 unknown prima
## Abstract ## Background. Muscle wasting and weight loss were observed when carcinomas were induced in a murine model of head and neck squamous cell carcinomas. Our hypothesis was C3H/HeN mice would develop evidence of cachexia when injected with tumor cells ## Methods. Ageβ and weightβmatched