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Simultaneous suppression of Src and signal transducer and activator of transcription 3 inhibits the growth of epithelial ovarian cancer cells

โœ Scribed by Lee, Shin-Wha; Yoo, Jin; Lee, Soo-Hyoung; Kim, Dongho; Kim, Yong-Man; Kim, Young-Tak


Book ID
123219532
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
923 KB
Volume
169
Category
Article
ISSN
0301-2115

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## Abstract Signal transducer and activator of transcription 3 (STAT3) is activated in a variety of human cancers, including ovarian cancer. The molecular mechanism by which the STAT3 is activated in cancer cells is poorly understood. We observed that human ovarian xenograft tumors (A2780) in mice