Simultaneous side effects of both clozapine and valproate
β Scribed by J. Nicolai; S. Smith; R. Keunen
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 26 KB
- Volume
- 27
- Category
- Article
- ISSN
- 1432-1238
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π SIMILAR VOLUMES
A mentally retarded 23-year-old woman with myoclonic astatic epilepsy developed an abnormal posture of extreme forward flexion, called camptocormia, during valproate monotherapy. Camptocormia occurred concomitantly with an increase of the plasma valproate level from about 330 mumol/l up to 530 mumol
Patients with essential tremor (ET) may not respond to commonly used drugs. Clozapine, an atypical neuroleptic drug, has been reported to improve postural Parkinson's disease tremor clinically resembling ET. The effects of a single dose of 12.5 mg clozapine and placebo were evaluated in a randomized