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Simultaneous quantitation of morphine, 6-acetylmorphine, codeine, 6-acetylcodeine and tramadol in hair using mixed-mode solid-phase extraction and gas chromatography–mass spectrometry

✍ Scribed by M. Barroso; M. Dias; D. N. Vieira; M. López-Rivadulla; J. A. Queiroz

Publisher
Springer
Year
2010
Tongue
English
Weight
301 KB
Volume
396
Category
Article
ISSN
1618-2650

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## Abstract A bioanalytical method using mixed‐mode solid phase extraction and UltraPerformance liquid chromatography‐tandem mass spectrometry (UPLC–MS/MS) was developed for the analysis of morphine, morphine‐3β‐glucuronide, morphine‐6β‐glucuronide, 6‐acetylmorphine, morphine __N__‐oxide, and 10‐hy