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Simultaneous quantification of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry

✍ Scribed by Walter J. Loos; Anne-Joy M. de Graan; Peter de Bruijn; Ron H.N. van Schaik; Marianne A.C. van Fessem; Mei-Ho Lam; Ron H.J. Mathijssen; Erik A.C. Wiemer


Book ID
108189829
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
487 KB
Volume
54
Category
Article
ISSN
0731-7085

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## Abstract Cyadox is a novel antimicrobial growth‐promoter of the quinoxalines. For food safety and pharmacokinetic studies, a convenient, sensitive and reproducible LC‐ESI‐MS/MS method was developed for the simultaneous determination of cyadox and its major metabolites, quinoxaline‐2‐carboxylic a