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Simultaneous qualitative assessment and quantitative analysis of flavonoids in various tissues of lotus (Nelumbo nucifera) using high performance liquid chromatography coupled with triple quad mass spectrometry

✍ Scribed by Sha Chen; Linchuan Fang; Huifen Xi; Le Guan; Jinbao Fang; Yanling Liu; Benhong Wu; Shaohua Li

Book ID: 116179464
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 767 KB
Volume: 724
Category: Article
ISSN: 0003-2670
DOI: 10.1016/j.aca.2012.02.051

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## Abstract A liquid chromatographic/tandem mass spectrometric (LC/MS/MS) assay for the quantitative analysis of the novel anticancer drug ABT‐518 and the screening of six potential metabolites in human plasma has been developed and validated to support a phase I study with the drug. ABT‐518 is an