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Simultaneous production of interleukin 6, interferon-β and colony-stimulating activity by fibroblasts after viral and bacterial infection

✍ Scribed by Jo Van Damme; M. Ronald Schaafsma; Willem E. Fibbe; J. H. Frederik Falkenburg; Ghislain Opdenakker; Alfons Billiau


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
576 KB
Volume
19
Category
Article
ISSN
0014-2980

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Interleukin 6 is secreted by breast fibr
✍ Eric F. Adams; B. Rafferty; M. C. White 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 472 KB

## Abstract Previous studies have demonstrated that cultured human breast fibroblasts secrete a high‐molecular‐weight polypeptide which stimulates the ability of human breast‐cancer MCF‐7 cells to convert oestrone (E1) to the biologically more active 17β‐oestradiol (E2). This effect is mediated by