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Simultaneous occurrence of lupus anticoagulant and factor VIII inhibitors

โœ Scribed by Triplett, Douglas A.

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
475 KB
Volume
56
Category
Article
ISSN
0361-8609

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โœฆ Synopsis

Granular acute lymphoblastic leukemia (ALL) is a morphological variant of ALL, and is characterized by the presence of prominent azurophilic granules or inclusions in the cytoplasm of the lymphoblasts. The prevalence of granular ALL ranges from 1.7 to 7% of all ALLs, depending on its definition in terms of percentage of blasts possessing granules [1][2][3][4]. Most series showed the predilection of common-ALL phenotype [1][2][3]. The presence of cytoplasmic granules in T-lineage leukemic blasts was rarely described [4,5]. We report here a case of childhood granular T-ALL.

A 7-year-old Chinese boy was admitted into the Department of Pediatrics at Prince of Wales Hospital in Hong Kong with a history of fever and pallor for a month, and subsequent symptoms of bleeding tendency. There was no family history of malignancy or blood disorder. Physical exami-

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