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Simultaneous measurements of tryptophan and its metabolites, kynurenine and serotonin, in the superficial layers of the spinal dorsal horn. A study in normal and arthritic rats

✍ Scribed by F. Godefroy; W.R. Matson; P.H. Gamache; J. Weil-Fugazza

Book ID: 115800347
Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 438 KB
Volume: 526
Category: Article
ISSN: 0006-8993
DOI: 10.1016/0006-8993(90)90267-f

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Serotonin (5HT), its chief metabolite 5-hydroxyindoleacetic acid (5 HIAA), its precursor tryptophan, and kynurenine, another metabolite of tryptophan, have been measured in post mortem human brain samples. Concentrations of these metabolites were not found to be significantly different in putamen, h