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Simultaneous Imaging of Vesicle Trafficking and Calcium-Mediated Exocytosis in Pancreatic Beta-Cells

โœ Scribed by Piston, David W.; Elliott, Amicia D.; Ustione, Alessandro


Book ID
122118354
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
36 KB
Volume
104
Category
Article
ISSN
0006-3495

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The present study demonstrates the action of the hypoglycaemic drugs repaglinide and glibenclamide in cultured newborn rat islet cells and mouse flTC3 cells. In cell-attached membrane patches of newborn rat islet cells repaglinide (10 nmol/ 1) and glibenclamide (20 nmol/1) decrease the open probabil