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Simultaneous diffusion and metabolism of betamethasone 17-valerate in the living skin equivalent

โœ Scribed by Kiyoshi Kubota; John Ademola; Howard I. Maibach

Book ID
102409981
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
440 KB
Volume
84
Category
Article
ISSN
0022-3549

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๐Ÿ“œ SIMILAR VOLUMES

Significance of viable skin layers in pe
Significance of viable skin layers in percutaneous permeation and its implication in mathematical models: Theoretical consideration based on parameters for betamethasone 17-valerate
โœ Kiyoshi Kubota; Howard I. Maibach ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 721 KB

The role of viable skin layers (viable epidermis and dermis) is examined by the three-layer model using parameter values for betamethasone 17-valerate. The mathematical three-layer diffusion model indicates that the lag time and half-life after vehicle removal in epidermis and split-thickness skin a