𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Simultaneous determination of thirteen plant alkaloids in a human specimen by SPE and HPLC

✍ Scribed by Jörg Pietsch; Jana Günther; Thomas Henle; Jan Dreßler

Book ID
102927709
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
888 KB
Volume
31
Category
Article
ISSN
1615-9306

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A new screening method for the simultaneous determination of thirteen plant alkaloids (aconitine, anabasine, atropine, brucine, colchicine, cotinine, cytisine, harmine, ibogaine, nicotine, scopolamine, strychnine, yohimbine) in a human specimen was developed based on solid‐phase extraction and reversed‐phase liquid chromatography with photodiode array detection. The validated method enables selective identification as well as accurate and sensitive quantification. The analysis of forensic and clinical samples emphasizes the applicability for intoxications and drug abuse, as well as for compliance control.

📜 SIMILAR VOLUMES

Simultaneous determination of maraviroc
Simultaneous determination of maraviroc and raltegravir in human plasma by HPLC-UV
✍ Stefania Notari; Chiara Tommasi; Emanuele Nicastri; Rita Bellagamba; Massimo Tem 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 145 KB

## Abstract Therapeutic drug monitoring is pivotal to improve the management of HIV infection. Here, a new HPLC–UV method to quantify simultaneously maraviroc and raltegravir levels in human plasma is reported. Remarkably, this is the first method for maraviroc determination in human plasma. The vo