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Simultaneous Determination of Salsolinol Enantiomers and Dopamine in Human Plasma and Cerebrospinal Fluid by Chemical Derivatization Coupled to Chiral Liquid Chromatography/Electrospray Ionization-Tandem Mass Spectrometry

✍ Scribed by Lee, Jeongrim; Huang, Bill X.; Yuan, Zhixin; Kim, Hee-Yong

Book ID: 121082377
Publisher: American Chemical Society
Year: 2007
Tongue: English
Weight: 193 KB
Volume: 79
Category: Article
ISSN: 0003-2700
DOI: 10.1021/ac0715827

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## Abstract A simple, sensitive and rapid high‐performance liquid chromatography/electrospray ionization tandem mass spectrometry method was developed and validated for the assay of granisetron in human plasma. Following liquid–liquid extraction, the analytes were separated using an isocratic mobil