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Simultaneous determination of plasma phenytoin and its primary hydroxylated metabolites in carbon tetrachloride-intoxicated rats by high-performance liquid chromatography

✍ Scribed by Einosuke Tanaka; Namiko Sakamoto; Miyuki Inubushi; Shogo Misawa

Publisher
Elsevier Science
Year
1995
Weight
307 KB
Volume
673
Category
Article
ISSN
0378-4347

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## Abstract Aceclofenac {[2‐(2′,6′‐dichlorophenyl)amino]phenylacetoxyacetic acid} is a phenylacetic acid derivative with potent analgesic and anti‐inflammatory properties and an improved gastro‐intestinal tolerance. In the present study, a liquid–liquid extraction‐based reversed‐phase HPLC method w