𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Simultaneous determination of plasma and urinary carcinoembryonic antigen levels

✍ Scribed by C. P. Karakousis; E. D. Holyoke; T. M. Chu

Book ID
102438475
Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
257 KB
Volume
7
Category
Article
ISSN
0022-4790

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✦ Synopsis

Abstract

The results of simultaneous plasma and urinary CEA levels in 14 patients are described. The aim was to determine whether urinary CEA derived from plasma or arose independently in the urinary tract. The method of reductio ad absurdum is followed. It is assumed that CEA in the urine is derived from plasma, and CEA clearance values for each patient are calculated. These varied widely from zero to a theoretical infinity. On this basis and from previous experimental evidence, it is concluded that urine is independent of plasma CEA. The finding, however, in some individuals of β€œanti‐CEA” ‐like factor(s) distorting urinary CEA determinations makes for some reservations about the safety of the conclusion. It is, however, certain that with the presently available technology, present urinary and plasma CEA values cannot be correlated.

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