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Simultaneous determination of pancuronium, vecuronium and their related compounds using LC–ESI-MS

✍ Scribed by Kiyotaka Usui; Takanori Hishinuma; Hiroaki Yamaguchi; Toshihide Saga; Toshihiro Wagatsuma; Kunihiko Hoshi; Naoki Tachiiri; Kuniaki Miura; Junichi Goto

Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
138 KB
Volume
8
Category
Article
ISSN
1344-6223

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## Abstract A specific and automated method was developed to quantify the anticonvulsants gabapentin, pregabalin and vigabatrin simultaneously in human serum. Samples were prepared with a protein precipitation. The hydrophilic interaction chromatography (HILIC) with a mobile phase gradient was used