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Simultaneous determination of imidazoleacetic acid and nτ-and nπ-methylimidazoleacetic acids in human urine by high-performance liquid chromatography with fluorescence detection

✍ Scribed by Yasuto Tsuruta; Hisao Tomida; Kazuya Kohashi; Yosuke Ohkura

Book ID
107996655
Publisher
Elsevier Science
Year
1987
Weight
444 KB
Volume
416
Category
Article
ISSN
0378-4347

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We have developed a liquid chromatographic method which uses electrochemical detection for the simultaneous quantitation of histamine and N'-methylhistamine in rat brain. The amines are derivatized with the water-soluble Bolton-Hunter reagent (sulfo B-H). Perchloric acid extracts of rat brains are c