Simultaneous Determination of Ascorbic Acid and Uric Acid by Using a PVC/TTF-TCNQ Composite Electrode as Detector in a FIA System
✍ Scribed by Manuel Cano; Beatriz Palenzuela; J. Luis Ávila; Rafael Rodríguez-Amaro
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 107 KB
- Volume
- 19
- Category
- Article
- ISSN
- 1040-0397
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✦ Synopsis
Abstract
A PVC/TTF‐TCNQ composite electrode has been employed as detector in a flow injection system. The proposed method allows the simultaneous detection of ascorbic acid (AA) and uric acid (UA) in mixtures by using a FIA system in a simple manner, without pre‐treatment or modified electrode. This method is based on the amperometric determination of (a) ascorbic acid at 0.15 V and (b) both analytes at 0.35 V, being the response linear in the range 1×10^−2^–4×10^−4^ M for both analytes with detection limits (S/N=3) of 1.2×10^−4^ M and 8.1×10^−5^ M for AA and UA, respectively.