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Simultaneous determination of amitriptyline, nortriptyline and four hydroxylated metabolites in serum by capillary gas-liquid chromatography with nitrogen-phosphorus-selective detection

✍ Scribed by S. Ulrich; T. Isensee; U. Pester

Publisher
Elsevier Science
Year
1996
Weight
600 KB
Volume
685
Category
Article
ISSN
0378-4347

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A selective and sensitive method for the determination of protein and non-protein amino acids by capillary gas chromatography (GC) has been developed. The amino acids were converted into their N(O,S)-isobutoxycarbonyl methyl ester derivatives and measured by GC with nitrogen-phosphorus selective det