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Simultaneous determination of all-trans-, 13-cis-, 9-cis-retinoic acid and their 4-oxo-metabolites in plasma by high-performance liquid chromatography

✍ Scribed by Beatrice Disdier; Hot Bun; Jacques Catalin; Alain Durand

Publisher
Elsevier Science
Year
1996
Weight
603 KB
Volume
683
Category
Article
ISSN
0378-4347

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## Abstract Since retinoic acid (RA) and RA receptors are key developmental regulators during organogenesis, they might participate in the abnormal development of the prostate caused by early estrogen exposure. In order to test this assumption, a sensitive analytical method that can differentiate 9