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Simultaneous detection of DNA length and sequence variations by liquid chromatography electrospray ionization time-of-flight mass spectrometry

✍ Scribed by H. Oberacher; H. Niederstätter; B. Casetta; W. Parson


Book ID
116538696
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
67 KB
Volume
1288
Category
Article
ISSN
0531-5131

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✍ Ajai K. Chaudhary; Munetaka Nokubo; Thomas D. Oglesby; Lawrence J. Marnett; Ian 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 678 KB

## Abstract Endogenous carcinogens arising from normal metabolism are known to cause modifications to DNA by reacting with bases to form adducts. Malondialdehyde is a well characterized endogenous carcinogen that forms an adduct with 2′‐deoxyguanosine. This adduct has been detected in rat and human