Immunostimulatory CpG DNA was self-assembled to form DNA hydrogels for use as a sustained delivery system for both intercalated doxorubicin (DXR) and immunostimulatory CpG motifs for cancer treatment. X-shaped DNA (X-DNA) was designed as a building unit, and underwent ligation to form DNA hydrogels.
โฆ LIBER โฆ
Simultaneous delivery of doxorubicin and immunostimulatory CpG motif to tumors using a plasmid DNA/doxorubicin complex in mice
โ Scribed by Yumiko Mizuno; Tomoyuki Naoi; Makiya Nishikawa; Sakulrat Rattanakiat; Nobuko Hamaguchi; Mitsuru Hashida; Yoshinobu Takakura
- Book ID
- 113693073
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 629 KB
- Volume
- 141
- Category
- Article
- ISSN
- 0168-3659
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