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Simultaneous application of the vascular endothelial growth factor (VEGF) receptor inhibitor PTK787/ZK 222584 and ionizing radiation does not further reduce the growth of canine oral melanoma xenografts in nude mice

✍ Scribed by Natalie Inteeworn; Stefanie Ohlerth; Gisele Höpfl; Franco Guscetti; Carla Rohrer Bley; Melanie C. Wergin; Malgorzata Roos; Max Gassmann; Barbara Kaser-Hotz

Book ID: 113939033
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 466 KB
Volume: 173
Category: Article
ISSN: 1090-0233
DOI: 10.1016/j.tvjl.2007.03.001

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## Abstract Assessment of tumour vascularity may characterize malignancy as well as predict responsiveness to anti‐angiogenic therapy. Non‐invasive measurement of tumour perfusion and blood vessel permeability assessed as the transfer constant, __K__^trans^, can be provided by dynamic contrast‐enha