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Simultaneous absence of the human IgG1, IgG2, IgG4 and IgA1 subclasses: Immunological and immunogenetical considerations

✍ Scribed by Gérard Lefranc; Hassen Chaabani; Erna Van Loghem; Marie-Paule Lefranc; Gerda De Lange; Ahmed-Noureddine Helal


Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
515 KB
Volume
13
Category
Article
ISSN
0014-2980

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✍ Taisiya A. Parkhomenko; Galina A. Legostaeva; Boris M. Doronin; Valentina N. Bun 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 359 KB

## Abstract We present the first evidence demonstrating that small fractions of IgGs of all four subclasses (IgG1–IgG4) are catalytically active in the hydrolysis of DNA and on average their relative activity (nM supercoiled DNA/1mg IgG/1 h) increases in the order: IgG1 (0.58) < IgG2 (0.94) < IgG3