## Abstract Helix βcapping motifs are believed to play an important role in stabilizing Ξ±βhelices and defining helix start and stop signals. We performed microsecond scale Brownian dynamics simulations to study ten XAAD sequences, with X = (A,E,I,L,N,Q,S,T,V,Y), to examine their propensity to form
Simulation of the dynamics of depth filtration of non-Brownian particles
β Scribed by V. N. Burganos; E. D. Skouras; C. A. Paraskeva; A. C. Payatakes
- Publisher
- American Institute of Chemical Engineers
- Year
- 2001
- Tongue
- English
- Weight
- 367 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0001-1541
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β¦ Synopsis
Abstract
A new simulator for flow of aqueous suspensions and deposition of nonβBrownian particles in granular media can predict the pattern of deposition and concomitant reduction in permeability as functions of depth, time and system parameters. The porous structure of the granular medium represented as a 3βD network of constricted pores considers the convergingβdiverging character of flow within pores. Using Lagrangianβtype simulation the particle deposition rate was calculated. Gravity and drag, as well as hydrodynamic and physicochemical interactions between suspended particles and pore walls, were considered in calculating 3βD particle trajectories. Deposit configurations were computed, and the evolution of the pore structure was simulated at discrete time steps. Changes in the pore geometry and nature of the collector surface affect flow and trajectory computations directly. Clusters of deposited particles were allowed to become reentrained if exposed to shear stress higher than a critical value. Reentrained clusters, which moved through downstream pores, might redeposit downstream at suitable sites and cause clogging of sufficiently narrow pores. Particle clusters clogging pores have a finite permeability, which significantly affects the system's transient behavior. Clogged pores act as collectors of solitary particles and of reentrained clusters, and substantially affect the transient behavior of the filter. The loss of permeability was monitored by calculating pore and network hydraulic conductance at each time step. Numerical results for the loss of permeability, temporal evolution of filter efficiency, and specific deposit profiles are based on suspension flow simulations in a typical granular porous medium.
π SIMILAR VOLUMES
Simulation results for the two-needle chain. (}): F F ΓΓ°m;gΓ m 0 and A = 1. (): F F ΓΓ°m;gΓ m 0 and A = 1.5. (F): F F ΓΓ°m;gΓ ΒΌ 0. The solid lines are the analytical result given by Equation ( ).