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Simulation of radio-frequency field inhomogeneity effects: application to pulse trains aimed at the determination of CSA–dipolar interference terms

✍ Scribed by Sébastien Leclerc; Sabine Bouguet-Bonnet; Pierre Mutzenhardt; Jean Brondeau; Daniel Canet


Book ID
102525936
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
160 KB
Volume
41
Category
Article
ISSN
0749-1581

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✦ Synopsis


Abstract

The cross‐correlation relaxation rate constant between dipolar interaction and chemical shift anisotropy (interference term) is of considerable interest for structural and dynamical determinations. The present study focuses on methods related to its impact on longitudinal nuclear relaxation, and especially to a procedure based on the applications of a train of π pulses applied to both nuclei involved in such a process (Levitt MH, Di Bari L. Bull. Magn. Reson. 1994; 16: 94–114). The resulting steady state leads, in principle, to a straightforward determination of the relevant interference term. Simulations taking into account inhomogeneity of the radio‐frequency (RF) field show that artifacts are responsible for instabilities which in practice preclude such a determination. An alternative method making use of a very limited number of RF pulses, combined with an appropriate filter, proves to be rather robust in view of achieving a proper measurement of the required interference term. Copyright © 2003 John Wiley & Sons, Ltd.