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Simulation of drug uptake in a two compartmental fractional model for a biological system

✍ Scribed by Ivo Petráš; Richard L. Magin

Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
342 KB
Volume
16
Category
Article
ISSN
1007-5704

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✦ Synopsis

This paper presents a very effective numerical method for the solution of the two-compartmental pharmacokinetic model for oral drug administration. This model consists of a set of two fractional order differential equations which connect the two compartments. The first compartment represents the gut while the second compartment corresponds to the drug concentration in the target tissue. For ease of computation, the numerical solution is also created as a Matlab function.

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