Simulation of all-proton relaxation curves as a means to elucidate molecular conformation in solution

Deuterium substitution effect on proton

Deuterium substitution effect on proton relaxation times as a direct means for elucidating molecular interaction in solution. An application to 2′,3′-isopropylideneadenosine

✍ Kazuyuki Akasaka; Toshiaki Imoto; Hiroyuki Hatano 📂 Article 📅 1973 🏛 Elsevier Science 🌐 English ⚖ 243 KB

Aoton T1 measurement with the Fourier transform method combined with quenching of dipolar coupling through s-elective deuterium substitution is shown to be a useful method for elucidating intra-and intermolecular interactions in solution, with 2', 3'4sopropylideneadenosine as an example. Average dis