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Simulation of a cell cycle model of slowly growing Eschericha coli cells

✍ Scribed by Dr. W. A. Knorre; H. Müller; Z. Simon

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
383 KB
Volume
13
Category
Article
ISSN
0233-111X

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✦ Synopsis

Abstract

A threshold concentration model for bacterial cells corresponding to the slow growth conditions studied by Kubitschek et al. (1967) was simulated on an analog computer. The stability of the model and the range of parameter values which reproduce the slow growth characteristics were studied. A characteristic of our model is the great oscillation of the DNA‐precursor pool whose synthesis is assumed to be subject to self‐inhibition. This periodic process is the basis of cell division in our model. Some modifications to rapid growth are also discussed.

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