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Simulation and prediction of clinical states of leukemia by the auto-regression model

✍ Scribed by H. Mori; S. Kitamura; T. Nagaoka; A. Takekawa; N. Yamaguchi

Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
336 KB
Volume
24
Category
Article
ISSN
0378-4754

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✦ Synopsis

The Auto-Regression method was applied to the modelling of leukemic states. The number of two kinds of normal cells and of a kind of abnormal cells in the peripheral blood were taken as output variable. The model obtained explained the trend of the normal cells in the prediction , while it could not satisfactorily follow the time course of abnormal leukemic cells. Therefore, the differential equation model based on the knowledge on the drug effect to the abnormal cells was constructed. The conbination of these two models seems to be feasible for describing the dynamics of leukemic states.

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