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Simulated weightlessness changes the cytoskeleton and extracellular matrix proteins in papillary thyroid carcinoma cells

✍ Scribed by Manfred Infanger; Peter Kossmehl; Mehdi Shakibaei; Johann Bauer; Stephanie Kossmehl-Zorn; Augusto Cogoli; Francesco Curcio; Alexander Oksche; Markus Wehland; Reinhold Kreutz; Martin Paul; Daniela Grimm

Book ID: 106139000
Publisher: Springer-Verlag
Year: 2006
Tongue: English
Weight: 670 KB
Volume: 324
Category: Article
ISSN: 0302-766X
DOI: 10.1007/s00441-005-0142-8

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Hyperthermia is reported to act as a sensitizer to chemotherapeutic drugs in the treatment of cancer. Thyroid follicular carcinoma were used to elucidate the effects of hyperthermic treatment (41-43°C) on cell morphology, cytoskeleton, and the focal adhesion complex. The critical temperature that re