Simplified quantitation of activated transcription factors
β Scribed by Challis, Bart; Heyman, John A; Baer, Sarah; Wasden, Chris
- Book ID
- 109937994
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 298 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1552-4450
- DOI
- 10.1038/nmeth907
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## Abstract Runx proteins are essential for a number of developmental processes and are aberrantly expressed in many human cancers. Runx factors bind DNA and coβfactors to activate or repress genes crucial for bone formation, hematopoiesis, and neuronal development. Coβactivator activator (CoAA) is