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Simplified PET measurement for evaluating histamine H1 receptors in human brains using [11C]doxepin

โœ Scribed by Hideki Mochizuki; Yuichi Kimura; Kenji Ishii; Keiichi Oda; Toru Sasaki; Manabu Tashiro; Kazuhiko Yanai; Kiichi Ishiwata

Book ID
116798809
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
782 KB
Volume
31
Category
Article
ISSN
0969-8051

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Dose dependency of brain histamine H1 re
Dose dependency of brain histamine H1 receptor occupancy following oral administration of cetirizine hydrochloride measured using PET with [11C]doxepin
โœ Manabu Tashiro; Motohisa Kato; Masayasu Miyake; Shoichi Watanuki; Yoshihito Funa ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 250 KB

## Aims: The strength of sedation due to antihistamines can be evaluated using positron emission tomography (pet). the purpose of the present study is to measure histamine h(1) receptor (h(1)r) occupancy following oral administration of cetirizine (10 and 20 mg) in order to examine dose dependency.