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Simplified formulae for the BIQUE estimation of variance components in disjunctive observation groups

โœ Scribed by N. Crocetto; M. Gatti; P. Russo


Publisher
Springer-Verlag
Year
2000
Tongue
English
Weight
148 KB
Volume
74
Category
Article
ISSN
1432-1394

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Properties of the estimated variance com
โœ Laszlo Endrenyi; Nathan Taback; Laszlo Tothfalusi ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 116 KB ๐Ÿ‘ 3 views

Characteristics of the variance component for the subject-by-formulation interaction ( 2 D ), estimated in simulated studies of individual bioequivalence and in three-and four-period cross-over trials reported by the FDA, were compared. 2 D was estimated by (i) restricted maximum likelihood (REML) a