Simple synthesis of [1-11C]acetate
✍ Scribed by D. Le Bars; M. Malleval; F. Bonnefoi; C. Tourvieille
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- French
- Weight
- 148 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
[1‐^11^C]Acetate is prepared by carboxylation of a Grignard reagent, CH~3~MgBr, on a simple polyethylene loop with cyclotron‐produced [^11^C]carbon dioxide, followed by hydrolysis and purification on solid‐phase extraction cartridges. Copyright © 2006 John Wiley & Sons, Ltd.
📜 SIMILAR VOLUMES
N a t i o n a l Laboratory, Upton, NY 11973 Received Sumary A r a p i d , one-pot, s y n t h e s i s of cyclopropane [ llC]carbonyl c h l o r i d e was developed. This s y n t h e s i s proceeded i n 807; r a d i ochemical y i e l d (EOB) i n a s y n t h e s i s time of LO minutes. This a c i d c h
## Abstract The ^11^C‐labelling of the taxane derivative BAY 59‐8862 (**1**), a potent anticancer drug, was carried out as a module‐assisted automated multi‐step synthesis procedure. The radiotracer **[^11^C]1** was synthesized by reacting [1‐^11^C]acetyl chloride (**6**) with the lithium salt of t
The paper describes the first method for n.c.a. "C-ring labelling of benzenoid compounds having a reactive group for further derivatization by use of the known principle of synchronous six-electron cyclization of hexatriene systems into aromatics. Nitro-["Clmethane (1) prepared from cyclotron-produc
## Abstract 3‐Indolylacetic acid (IAA) is the major auxin in higher plants and plays a key role in plant growth and development. We report the rapid radiolabeling of the important plant hormone using carbon‐11 (half life: 20.4 min) enabling __in vivo__ imaging of its distribution and movement in wh