𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Simple synthesis of [1-11C]acetate

✍ Scribed by D. Le Bars; M. Malleval; F. Bonnefoi; C. Tourvieille


Publisher
John Wiley and Sons
Year
2006
Tongue
French
Weight
148 KB
Volume
49
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

[1‐^11^C]Acetate is prepared by carboxylation of a Grignard reagent, CH~3~MgBr, on a simple polyethylene loop with cyclotron‐produced [^11^C]carbon dioxide, followed by hydrolysis and purification on solid‐phase extraction cartridges. Copyright © 2006 John Wiley & Sons, Ltd.


📜 SIMILAR VOLUMES


Synthesis of [1-11C]phenol
✍ P. Mäding; J. Steinbach 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 214 KB
A simple one-pot synthesis of cyclopropa
✍ Daniel W. McPherson; Dah-Ren Hwang; Joanna S. Fowler; Alfred P. Wolf; Robert M. 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 French ⚖ 353 KB

N a t i o n a l Laboratory, Upton, NY 11973 Received Sumary A r a p i d , one-pot, s y n t h e s i s of cyclopropane [ llC]carbonyl c h l o r i d e was developed. This s y n t h e s i s proceeded i n 807; r a d i ochemical y i e l d (EOB) i n a s y n t h e s i s time of LO minutes. This a c i d c h

Synthesis of a 11C-labelled taxane deriv
✍ P. Mäding; J. Zessin; U. Pleiß; F. Füchtner; F. Wüst 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 173 KB

## Abstract The ^11^C‐labelling of the taxane derivative BAY 59‐8862 (**1**), a potent anticancer drug, was carried out as a module‐assisted automated multi‐step synthesis procedure. The radiotracer **[^11^C]1** was synthesized by reacting [1‐^11^C]acetyl chloride (**6**) with the lithium salt of t

N.C.A. 11C-labelling of benzenoid compou
✍ J. Steinbach; P. Mäding; F. Füchtner; B. Johannsen 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 400 KB

The paper describes the first method for n.c.a. "C-ring labelling of benzenoid compounds having a reactive group for further derivatization by use of the known principle of synchronous six-electron cyclization of hexatriene systems into aromatics. Nitro-["Clmethane (1) prepared from cyclotron-produc

Radiosynthesis of C-11 labeled auxin (3-
✍ Alicia E. Reid; Sung Won Kim; Brienne Seiner; Frank W. Fowler; Jacob Hooker; Ric 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 193 KB 👁 1 views

## Abstract 3‐Indolylacetic acid (IAA) is the major auxin in higher plants and plays a key role in plant growth and development. We report the rapid radiolabeling of the important plant hormone using carbon‐11 (half life: 20.4 min) enabling __in vivo__ imaging of its distribution and movement in wh