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Simple strategy for bone regeneration with a BMP-2/7 gene expression cassette vector

✍ Scribed by Mariko Kawai; Hiroki Maruyama; Kazuhisa Bessho; Hiromitsu Yamamoto; Jun-Ichi Miyazaki; Toshio Yamamoto

Book ID: 116299378
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 1013 KB
Volume: 390
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2009.10.099

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## Abstract Bone morphogenetic proteins (BMPs) have demonstrated effectiveness as bone regeneration agents whether delivered as recombinant proteins or via gene therapy. Current gene therapy approaches use vectors expressing single BMPs. In contrast, multiple BMPs are coordinately expressed during