๐”– Bobbio Scriptorium
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Simple procedure for determining octanol-aqueous partition, distribution, and ionization coefficients by reversed-phase high-pressure liquid chromatography

โœ Scribed by Stefan H. Unger; James R. Cook; John S. Hollenberg


Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
497 KB
Volume
67
Category
Article
ISSN
0022-3549

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Newly defined lipophilic indexes, log k', of a series of penicillins and cephalosporins were rapidly and reliably determined by reversed-phase high-pressure liquid chromatography (HPLC) on bonded octadecylsilane supports. The log k' values obtained from their retention times exhibited a linear relat