Simple preparations of N-(tert-butyloxycarbonyl)-O-methyl-L-serine and N-(tert-butyloxycarbonyl)-O-methyl-L-threonine by direct methylation
β Scribed by Chen, Francis M. F.; Benoiton, N. Leo
- Book ID
- 127080720
- Publisher
- American Chemical Society
- Year
- 1979
- Tongue
- English
- Weight
- 329 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
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The paper describes the synthesis of two epimeric tdpeptides &(L-cx-aminoadipoyl)-L-cysteinyI-D-(Omethyl)-D-threonine (13) and &(L-ct-aminoadipoyl)-L-cysteinyl-D-(O-methyl)-D-allothreonine ( 14), modified substrates for the isopenicillin-N synthase enzyme. The D-allothreonine tripeptide ( 14) has be