✦ LIBER ✦

Simple model for NMR relaxation times of flexible molecules in solution

✍ Scribed by M. Baldo; A. Grassi

Publisher: John Wiley and Sons
Year: 1989
Tongue: English
Weight: 605 KB
Volume: 27
Category: Article
ISSN: 0749-1581
DOI: 10.1002/mrc.1260270605

No coin nor oath required. For personal study only.

✦ Synopsis

The motion of a flexible molecule in solution can be described as a Brownian motion between the different conformations that the molecule can assume. Each conformation corresponds to a local minimum of the energy surface.

A simple model is given for this type of motion in relation to nuclear magnetic resonance (NMR) relaxation measurements. This is based only on the assumption that the diffusion tensor for the overall tumbling is not appreciably affected by jumping between the different conformations. The limits of the model are discussed and an illustrative application to 2-fluorobutane is given.

📜 SIMILAR VOLUMES

Application of 1H NMR bi-selective relax

Application of 1H NMR bi-selective relaxation times to conformational analysis in solution

✍ Makiko Sugiura; Narao Takao; Hideaki Fujiwara 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 483 KB

The usefulness of 'H bi-selective relaxation times ( 2 ' : ' ) and selective relaxation times (T,') for structure and conformation determination is emphasized. A pulse sequence has been devised which provides the apparent observed T : ' . The cross-relaxations (q,) or Fi, values are derived from the

Modeling of Self-Diffusion and Relaxatio

Modeling of Self-Diffusion and Relaxation Time NMR in Multi-Compartment Systems

✍ Eugene G. Novikov; Dagmar van Dusschoten; Henk Van As 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 127 KB

The theory of pulsed field gradient (pfg) NMR applied to molecules in cellular systems which contain different subcellular compartments separated by permeable membranes, acting as diffusion barriers, has been extended. A numerical model of restricted diffusion and magnetization relaxation behavior i

Application of 1H NMR selective and bise

Application of 1H NMR selective and biselective relaxation times. III—conformational analysis of quinidine in solution

✍ Torei Sai; Narao Takao; Makiko Sugiura 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 380 KB 👁 1 views

## Abstract A relaxation method was applied to quinidine (1) where cross‐relaxations (σ~ij~) were obtained by ^1^H selective and biselective __T__~1~ measurements and correlation times for molecular reorientation (τ~c~) were evaluated from the frequency dependence of the non‐selective __T__~1.~ The

NMR relaxation of water in hydrogel poly

NMR relaxation of water in hydrogel polymers: A model for tissue

✍ John C. Gore; Mark S. Brown; Jianhui Zhong; K. Fritz Mueller; William Good 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 395 KB 👁 1 views

The NMR relaxation rates ofa class of hydrated polymers (hydrogels) have been investigated over a wide range of frequencies (0.01 to 60 MHz) and compositions. The gels comprise long chains of polytetramethylene oxide diol crosslinked by copolymers of dimethylacrylamide and methylmethacrylate. The lo

Modelling of Self-diffusion and Relaxati

Modelling of Self-diffusion and Relaxation Time NMR in Multicompartment Systems with Cylindrical Geometry

✍ Louise van der Weerd; Sergey M. Melnikov; Frank J. Vergeldt; Eugene G. Novikov; 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 228 KB

Multicompartment characteristics of relaxation and diffusion in a model for (plant) cells and tissues have been simulated as a means to test separating the signal into a set of these compartments. A numerical model of restricted diffusion and magnetization relaxation behavior in PFG-CPMG NMR experim

31P NMR relaxation time studies of 2,3-d

31P NMR relaxation time studies of 2,3-diphosphoglycerate in solution and intact erythrocytes

✍ Marianne Christensen; Jens Peter Jacobsen 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 393 KB

The 31P T1 spin-lattice relaxation times and nuclear Overhauser effects of 3-P and 2-P in 2,3-diphosphoglycerate (2,3-DPG) have been measured in pure water solutions and in suspensions of intact erythrocytes. It was found that extremely careful purification of the water solutions from paramagnetic i