Simple, economical and environmentally friendly sulfone synthesis

✍ Scribed by Diego A. Alonso; Carmen Nájera; Montserrat Varea

• Book ID: 104251016
• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 57 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)00598-1

✦ Synopsis

Chemoselective sulfur oxidation of functionalized sulfides was developed using catalytic amounts of MnSO 4 •H 2 O (1 mol%) and 30% H 2 O 2 in the presence of a buffer solution of NaHCO 3 . Aromatic and aliphatic sulfides were oxidized to sulfones in quantitative yields in 15 min. Different functional groups including double bonds, alcohols, ethers of THP and TBDMS groups were tolerated under these mild and green reaction conditions.