✦ LIBER ✦

Simple determination of relative hydrogen atom affinities by supercritical fluid chromatography/atmospheric pressure chemical ionization mass spectrometry

✍ Scribed by Kozo Matsumoto

Publisher: John Wiley and Sons
Year: 1994
Tongue: English
Weight: 230 KB
Volume: 29
Category: Article
ISSN: 1076-5174
DOI: 10.1002/oms.1210290510

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Coupled supercritical fluid chromatography and atmospheric pressure chemical ionization mass spectrometry was applied to estimate hydrogen atom affinities. The intensities of the M^+^ and MH^+^ peaks in the mass spectra were measured at various drift voltages (collision energies). The ratios of the two peaks were plotted against the drift voltages to obtain threshold drift voltages. The threshold drift voltages of polycyclic aromatic hydrocarbons were plotted and found to be proportional to the values of reported hydrogen atom affinities. The value for acenaphthylene was estimated to be 292.9 kJ mol^−1^ from this relationship.

📜 SIMILAR VOLUMES

Quantitative Determination of Amlodipine

Quantitative Determination of Amlodipine in Serum by Liquid Chromatography with Atmospheric Pressure Chemical Ionization Tandem Mass Spectrometry

✍ Yasuda, Taeko; Tanaka, Mitsuko; Iba, Kazuhiko 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 436 KB 👁 2 views

A sensitive and specific liquid chromatographic method coupled with tandem mass spectrometry was developed for the quantification of amlodipine in human and rat serum, which is a dihydropyridine derivative with calcium antagonist activity. An atmospheric pressure chemical ionization interface was us

Determination and quantitative analysis

Determination and quantitative analysis of alkaloids in Aconitum japonicum by liquid chromatography atmospheric pressure chemical ionization mass spectrometry

✍ Koji Wada; Hideo Bando; Norio Kawahara; Takao Mori; Mitsuo Murayama 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 458 KB 👁 1 views

Determination of furanic compounds in in

Determination of furanic compounds in insulating oil by high performance liquid chromatography/mass spectrometry using atmospheric pressure chemical ionization

✍ Orsolya Kóréh; Krisztina Ludányi; Károly Vékey; Eszter Jávorszky; Eszter Molnár; 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 96 KB 👁 2 views

A method has been developed to determine furanic compounds in insulating oil matrix using liquid chromatography/mass spectrometry with atmospheric pressure chemical ionization. The examined samples were provided from model experiments and also from several high voltage functioning transformers. To i

Molecular species of sphingomyelin: dete

Molecular species of sphingomyelin: determination by high-performance liquid chromatography/mass spectrometry with electrospray and high-performance liquid chromatography/tandem mass spectrometry with atmospheric pressure chemical ionization

✍ Karlsson, Anders Å.; Michélsen, Peter; Odham, Göran 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 144 KB 👁 3 views

In a sphingomyelin-enriched sample of polar lipids from bovine milk, molecular species of intact sphingomyelin were separated by normal-phase high-performance liquid chromatography and detected by mass spectrometry (MS) for structural information. First, by using electrospray with positive ionizatio

Determination of LY355703 in dog and mou

Determination of LY355703 in dog and mouse plasma by positive ion liquid chromatography/tandem mass spectrometry with atmospheric pressure chemical ionization

✍ Berna, M.; Shugert, R.; Mullen, J. 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 268 KB 👁 1 views

A liquid chromatographic/mass spectrometric assay was developed for the determination of LY355703, a potent anti-tumor drug, in mouse and dog plasma. Empore (3M) solid-phase extraction cartridges were used for C 18 sample preparation in conjunction with a positive pressure manifold. Chromatographic

Determination of L-654,066, a new 5α-red

Determination of L-654,066, a new 5α-reductase inhibitor in plasma by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry

✍ J. D. Gilbert; T. V. Olah; A. Barrish; T. F. Greber 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 480 KB

L-654,066 is a new 5 alpha-reductase inhibitor. A sensitive and specific assay based on combined liquid chromatography/mass spectrometry has been developed for the determination of this drug candidate in plasma. The analyte was isolated from plasma by solid-phase extraction on a C-18 cartridge. A re