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Simple detection of the inter-α-trypsin-inhibitor (ITI) polymorphism by isoelectric focusing with direct immunofixation

✍ Scribed by Anja Martin; A. Correns; Petra Otremba; G. Geserick

Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 172 KB
Volume: 73
Category: Article
ISSN: 0379-0738
DOI: 10.1016/0379-0738(95)01708-9

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✦ Synopsis

The inter-~-trypsin inhibitor (ITI) polymorphism was analysed in a German population, using polyacrylamide gel isoelectric focusing with subsequent direct immunofixation with monospecific ITI antisera. Gene frequencies of ITI* 1, ITI*2, ITI*3, and ITI*4 were calculated to be 0.6150, 0.3753, 0.0078 and 0.0019, respectively. In our study the allele ITI*4 is described for the first time in a German population.

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